A serious forgotten problem such as secondary bacterial pneumonia that follows influenza is reemerging. There are many fatal cases that arise after frequent complications of influenza. Nowadays there are known many treatments that are not very effective activating immune system and causing inflammation in the lungs. An appropriate therapeutic approach should be formulated in order to understand the contribution of the previous bacterial infection, the state of the immune system and how an invading bacteria influences on the organism. New alternative strategies of treatment and long term therapies targeted at pathogenous processes should be worked out as soon as possible in order to prevent or cope with dangerous fulminating infections. Hopefully, in the near future there will be many different and efficacious strategies of disarming pathogens without removing them.
Starting from 1930s there was only one common paradigm of bacterial pneumonia treatment that is based on quick and thorough killing of all harmful invading organisms. Despite existing novelties and our developed armamentarium secondary bacterial pneumonia remains to be a serious worldwide problem. The main reason of the existing problem is that influenza viruses worsen the disease severity all over the world and increase the necessity for clinical help in treatment of secondary bacterial pneumonia. Some time ago influenza and bacterial pneumonia were considered to be the 5th main cause of children’s death and the 7th cause for all other categories of people living in the Unites States. Many of us should have heard about the Spanish Flu pandemic that happened in 1918. At that time nearly 50 million people died and, moreover, many of them died of secondary bacterial pneumonia that was impossible to cure.
The world is developing these days and the problems do not disappear but they obtain new characteristics and forms. Nowadays there are many respiratory tract infections in the USA that can be fatal for children. But anyway we should also take into consideration the fact that children who live in developing countries are dying of secondary bacterial pneumonia 25 times more often than those living in the USA. Therefore, it is very urgent to think about new efficacious approaches and strategies that could change the present situation.
It is also known that in 1937 there was a very high level of mortality because of secondary bacterial pneumonia. It was discovered that it was better to cure infections separately with a certain period of recovery than when they were combined with other ones. Even when people invented antibiotics the situation didn’t change.
Many experiments were made on mice in order to verify specific hypotheses concerning the evaluation of new strategies of treatment for secondary bacterial pneumonia that follows influenza. Finally, it was found that traditional methods of treatment are not so effective as they should be. Despite the clearance of the bacteria from lungs, mice were not able to cope with pulmonary infections.
That is why the subject of secondary bacterial pneumonia treatment following influenza should be highlighted in the nearest time and many therapeutic investigations should be performed in order to show some good and advanced results.